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| Oral Sub-Mucosal Fibrosis ： ウィキペディア英語版 |
Oral submucous fibrosis
Oral submucous fibrosis (OSMF) is a chronic, complex potential potent pre-cancerous ( appox 20% may have chances ) condition characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues (lamina propria and deeper connective tissues). As the disease progresses, the jaws become rigid to the point that the sufferer is unable to open their mouth. The condition is linked to oral cancers and is associated with areca nut chewing, the main component of betel quid. Areca nut or betel quid chewing, a habit similar to tobacco chewing, is practiced predominantly in Southeast Asia and India, dating back thousands of years.
==History==
In 1952, J. Schwartz coined the term ''atrophica idiopathica mucosa oris'' to describe an oral fibrosing disease he discovered in five Indian women from Kenya. S.G. Joshi subsequently coined the termed oral submucous fibrosis (OSF) for the condition in 1953.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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